Recent data suggest alternative mechanisms that promote HLA-associated drug syndromes.

Abacavir binds within the antigen-binding cleft of human leukocyte antigen (HLA)-B*57:01. Read more about it here.

Read More

Molecular Mountaineers

UF drug development researchers are forging new trails to cancer treatments. Read about it here.

Read More

Drug Discovery

We use methods in structure-based drug design to discover and develop novel therapies for human diseases. We are actively targeting cardiovascular diseases, cancer and diabetes by high-throughput virtual screening combined […]

Read More
Prev Next

Contact Us

Nature ImmunologySubscribe to this RSS Feed

Does tissue imprinting restrict macrophage plasticity?

January 18, 2021

Nature Immunology, Published online: 18 January 2021; doi:10.1038/s41590-020-00849-2Based on the results of recent studies that have dissected the response of individual macrophage subsets to...

Gut CD4<sup>+</sup> T cell phenotypes are a continuum molded by microbes, not by T<sub>H</sub> archetypes

January 18, 2021

Nature Immunology, Published online: 18 January 2021; doi:10.1038/s41590-020-00836-7Helper T cell subsets are characterized functionally by the cytokines they produce. Benoist and colleagues...

Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

January 18, 2021

Nature Immunology, Published online: 18 January 2021; doi:10.1038/s41590-020-00848-3γδ T cells have potent effector functions through their production of IFN-γ or IL-17. Pennington and colleagues...

A fresh look at the T helper subset dogma

January 18, 2021

Nature Immunology, Published online: 18 January 2021; doi:10.1038/s41590-020-00858-1Single-cell-sequencing techniques enable the decades-old T helper subset dogma to be re-examined in an unsupervised...

γδ T cells suppress <i>Plasmodium falciparum</i> blood-stage infection by direct killing and phagocytosis

January 11, 2021

Nature Immunology, Published online: 11 January 2021; doi:10.1038/s41590-020-00847-4Junqueira et al. show that human γδ T cells control erythrocytic Plasmodium falciparum infection by multiple...