Recent data suggest alternative mechanisms that promote HLA-associated drug syndromes.

Abacavir binds within the antigen-binding cleft of human leukocyte antigen (HLA)-B*57:01. Read more about it here.

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Molecular Mountaineers

UF drug development researchers are forging new trails to cancer treatments. Read about it here.

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Drug Discovery

We use methods in structure-based drug design to discover and develop novel therapies for human diseases. We are actively targeting cardiovascular diseases, cancer and diabetes by high-throughput virtual screening combined […]

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Dysbiosis shapes vaccine responses

June 20, 2018

Dysbiosis shapes vaccine responsesDysbiosis shapes vaccine responses, Published online: 20 June 2018; doi:10.1038/s41590-018-0151-xDysbiosis shapes vaccine responses

Fiber against flu

June 20, 2018

Fiber against fluFiber against flu, Published online: 20 June 2018; doi:10.1038/s41590-018-0147-6Fiber against flu

Plasmacytoid dendritic cells: origin matters

June 20, 2018

Plasmacytoid dendritic cells: origin mattersPlasmacytoid dendritic cells: origin matters, Published online: 20 June 2018; doi:10.1038/s41590-018-0143-xPlasmacytoid dendritic cells (pDCs) are type I...

The E3 ligases Itch and WWP2 cooperate to limit T<sub>H</sub>2 differentiation by enhancing signaling through the TCR

June 20, 2018

The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCRThe E3 ligases Itch and WWP2 cooperate to limit T<sub>H</sub>2 differentiation by...

TILs on standby

June 20, 2018

TILs on standbyTILs on standby, Published online: 20 June 2018; doi:10.1038/s41590-018-0150-yTILs on standby