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Recent data suggest alternative mechanisms that promote HLA-associated drug syndromes.

Abacavir binds within the antigen-binding cleft of human leukocyte antigen (HLA)-B*57:01. Read more about it here.

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Molecular Mountaineers

UF drug development researchers are forging new trails to cancer treatments. Read about it here.

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Drug Discovery

We use methods in structure-based drug design to discover and develop novel therapies for human diseases. We are actively targeting cardiovascular diseases, cancer and diabetes by high-throughput virtual screening combined […]

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ILC2 commitment

June 18, 2015

Sirt-ainly Aire

June 18, 2015

Sirtuin-1 (Sirt1), a protein deacetylase known for its multiple cellular functions, including roles in metabolism, stress response and aging, is a post-translational modulator of autoimmune regulator...

About STATs

June 18, 2015

DNA methylation secures CD4+ and CD8+ T cell lineage borders

June 18, 2015

Dynamic control of DNA methylation in the Cd4 locus serves an important role in reinforcing the binary fate stability of helper and cytotoxic T cells.