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Recent data suggest alternative mechanisms that promote HLA-associated drug syndromes.

Abacavir binds within the antigen-binding cleft of human leukocyte antigen (HLA)-B*57:01. Read more about it here.

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Molecular Mountaineers

UF drug development researchers are forging new trails to cancer treatments. Read about it here.

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Drug Discovery

We use methods in structure-based drug design to discover and develop novel therapies for human diseases. We are actively targeting cardiovascular diseases, cancer and diabetes by high-throughput virtual screening combined […]

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Healing the CNS

February 17, 2015

LincRNA signatures in human lymphocytes

February 17, 2015

Sequencing studies have provided a comprehensive catalog of the expression of intergenic long noncoding RNAs (lincRNAs) in 13 subsets of human T cells and B cells. Subtype-selective lincRNAs are among...

Feeding immunity: skepticism, delicacies and delights

February 17, 2015

There are clear epidemiological links between nutrition and immunological function, but a dearth of mechanistic insights has made this topic controversial. Veldhoen and Veiga-Fernandes discuss this...

Profiling the diversity of innate lymphoid cells

February 17, 2015

Genome-wide transcriptional profiling of tissue-resident innate lymphoid cells (ILCs) has provided important insight not only into their developmental relationships and phenotypic plasticity but also...

Venom activity

February 17, 2015