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Recent data suggest alternative mechanisms that promote HLA-associated drug syndromes.

Abacavir binds within the antigen-binding cleft of human leukocyte antigen (HLA)-B*57:01. Read more about it here.

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Molecular Mountaineers

UF drug development researchers are forging new trails to cancer treatments. Read about it here.

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Drug Discovery

We use methods in structure-based drug design to discover and develop novel therapies for human diseases. We are actively targeting cardiovascular diseases, cancer and diabetes by high-throughput virtual screening combined […]

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Mitochondria provide a 'complex' solution to a bacterial problem

August 19, 2016

Adaptations in the mitochondrial electron-transport chain mediate antibacterial responses in macrophages.

Targeting natural killer cells in cancer immunotherapy

August 19, 2016

There is now a major effort to fully exploit the anti-tumor properties of NK cells in the clinic. In this Review, Smyth and colleagues detail recent advances in NK cell–based immunotherapies and...

Immunogenic cross-talk between dengue and Zika viruses

August 19, 2016

At least five recent papers have shown an unexpected antigenic relationship between Zika and dengue viruses, with potential implications for vaccines and therapeutics.

Protecting lymph nodes

August 19, 2016