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Recent data suggest alternative mechanisms that promote HLA-associated drug syndromes.

Abacavir binds within the antigen-binding cleft of human leukocyte antigen (HLA)-B*57:01. Read more about it here.

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Molecular Mountaineers

UF drug development researchers are forging new trails to cancer treatments. Read about it here.

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Drug Discovery

We use methods in structure-based drug design to discover and develop novel therapies for human diseases. We are actively targeting cardiovascular diseases, cancer and diabetes by high-throughput virtual screening combined […]

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Tetherin signaling

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Time to cast a larger net

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Neutrophils sense the size of microbial targets and respond via 'NETosis' when targets are too big to internalize and contain via phagocytosis.

Street smarts of science for students

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A workshop organized by the Society for Leukocyte Biology offers advice to graduate students on how to navigate educational and professional waters to find success in academia.

TCR signaling fuels Treg cell suppressor function

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Acute ablation of T cell antigen receptors (TCRs) in regulatory T cells (Treg cells) impairs the suppressive activity of these cells, even though they retain expression of Foxp3 and CD25. TCR...